Some molecules - ammonia, carbon dioxide, water - show up everywhere in the universe, whether life is present or not. But others pop up especially in the presence of life itself. Among the biomarkers in Earth's atmosphere are ozone-destroying chlorofluorocarbons from aerosol sprays, vapor from mineral solvents, escaped coolants from refrigerators and air conditioners, and smog from the burning of fossil fuels. No other way to read that list: sure signs of the absence of intelligence.

This preservation of favourable variations and the destruction of injurious variations, I call Natural Selection, or the Survival of the Fittest. Variations neither useful nor injurious would not be affected by natural selection and would be left a fluctuating element.

It is interesting thus to follow the intellectual truths of analysis in the phenomena of nature. This correspondence, of which the system of the world will offer us numerous examples, makes one of the greatest charms attached to mathematical speculations.

There cannot be a language more universal and more simple, more free from errors and obscurities...more worthy to express the invariable relations of all natural things [than mathematics]. [It interprets] all phenomena by the same language, as if to attest the unity and simplicity of the plan of the universe, and to make still more evident that unchangeable order which presides over all natural causes

We must be careful not to confuse data with the abstractions we use to analyse them.

The black holes of nature are the most perfect macroscopic objects there are in the universe: the only elements in their construction are our concepts of space and time.