Sometimes the probabilities are very close to certainties, but they're never really certainties

[N]o scientist likes to be criticized. ... But you don't reply to critics: "Wait a minute, wait a minute; this is a really good idea. I'm very fond of it. It's done you no harm. Please don't attack it." That's not the way it goes. The hard but just rule is that if the ideas don't work, you must throw them away. Don't waste any neurons on what doesn't work. Devote those neurons to new ideas that better explain the data. Valid criticism is doing you a favor.

While I'm a big fan of science fiction, especially as rendered in expensive Hollywood blockbusters, it's the real universe that calls to me.

Biology is now bigger than physics, as measured by the size of budgets, by the size of the workforce, or by the output of major discoveries; and biology is likely to remain the biggest part of science through the twenty-first century.

Let both sides seek to invoke the wonders of science instead of its terrors. Together let us explore the stars, conquer the deserts, eradicate disease, tap the ocean depths, and encourage the arts and commerce.

There may be many Big Bangs that happened at various and far-flung locations, each creating its own swelling, spatial expanse, each creating a universe - our universe being the result of only one of those Big Bangs.