What is it that keeps you so interested in the telomere? It's so intricate and complicated, and you want to know how it works.
Interpretation
The quote highlights the fascination with the complexity of telomeres and the desire to understand their function.
Elizabeth Blackburn's statement reflects the intrigue scientists feel towards telomeres, which are crucial for chromosome protection and cellular aging. Her pursuit to unravel the complexities of telomeres illustrates a broader theme in science: the motivation to explore and understand the intricate systems that govern life and health.
In practice
In a lecture on genetics, you might say, 'As Elizabeth Blackburn pointed out, what is it that keeps you so interested in the telomere?' to engage the audience.
Cancer cells have had so many other things go wrong with them, genetic, non-genetic changes, that those cells, one of the things they then get selected for is that they have lots of telomerase because now the telomeres in those cells get maintained.
We and other groups are seeing clear statistical links between telomere shortness and risk for a variety of diseases that are becoming very common, such as cardiovascular disease, diabetes and certain cancers.
Checking your telomere length is a bit like weighing yourself: you get this single number which depends on a lot of factors. Telomere length gives a sense of your underlying health.
We think there are lifestyle factors that boost telomerase naturally.
For me, arguably the story of telomeres and telomerase began thousands of years ago, in the cornfields of the Maya highlands of Central America.
If we think of our chromosomes - they carry our genetic material - as being like shoelaces, I work on the plastic tips at the end that protect them.
A great deal of my work is just playing with equations and seeing what they give.
Dissent is the native activity of the scientist, and it has got him into a good deal of trouble in the last years. But if that is cut off, what is left will not be a scientist. And I doubt whether it will be a man.
That which is not measurable is not science. That which is not physics is stamp collecting.
Science, my lad, has been built upon many errors; but they are errors which it was good to fall into, for they led to the truth.
As climate change moves from a model of the future to the reality of the present, health care systems across the country are facing a difficult set of questions. What are doctors supposed to do when wildfires, rising floodwater or other natural disasters threaten their ability to provide care for patients?
You know what they call alternative medicine that's been proved to work? - Medicine.
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