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No isolated experiment, however significant in itself, can suffice for the experimental demonstration of any natural phenomenon; for the "one chance in a million" will undoubtedly occur, with no less and no more than its appropriate frequency, however surprised we may be that it should occur to us.
Ronald Fisher
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Interpretation

What this quote means

No single experiment can prove a natural phenomenon, as rarity and frequency balance in nature.

Ronald Fisher emphasizes that individual experiments, no matter how groundbreaking, are not enough to demonstrate the validity of a natural phenomenon. He points out that unexpected outcomes, though surprising, are part of the natural order and will occur at their expected rates. This conveys the importance of replication and statistical validity in scientific research.

Themes

ExperimentPhenomenonFrequencyNaturalScience

In practice

Example use cases

In a scientific conference discussing the importance of experimental replication.

More from Ronald Fisher

I believe sanity and realism can be restored to the teaching of Mathematical Statistics most easily and directly by entrusting such teaching largely to men and women who have had personal experience of research in the Natural Sciences.
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To consult the statistician after an experiment is finished is often merely to ask him to conduct a post mortem examination. He can perhaps say what the experiment died of.
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