Tout est poison, rien n'est poison, tout est une question de dose. Everything is poisonous, nothing is poisonous, it is all a matter of dose.
Claude BernardRead
Now, a living organism is nothing but a wonderful machine endowed with the most marvellous properties and set going by means of the most complex and delicate mechanism.
Interpretation
Living organisms are intricate machines with remarkable abilities driven by complex mechanisms.
In this quote, Claude Bernard emphasizes the extraordinary nature of living organisms, likening them to machines but highlighting their complexity and the delicate systems that enable life. This perspective reflects the intricate arrangements of biological systems and the sophistication of life itself, challenging us to appreciate the marvels of nature and biology.
In practice
In a biology class discussing the nature of life and living systems.
Tout est poison, rien n'est poison, tout est une question de dose. Everything is poisonous, nothing is poisonous, it is all a matter of dose.
When a physician is called to a patient, he should decide on the diagnosis, then the prognosis, and then the treatment. ... Physicians must know the evolution of the disease, its duration and gravity in order to predict its course and outcome. Here statistics intervene to guide physicians, by teaching them the proportion of mortal cases, and if observation has also shown that the successful and unsuccessful cases can be recognized by certain signs, then the prognosis is more certain.
The goal of scientific physicians in their own science ... is to reduce the indeterminate. Statistics therefore apply only to cases in which the cause of the facts observed is still indeterminate.
Theories are like a stairway; by climbing, science widens its horizon more and more, because theories embody and necessarily include proportionately more facts as they advance.
True science teaches us to doubt and, in ignorance, to refrain.
The experimenter who does not know what he is looking for will not understand what he finds.
It used to be thought that our genes were historically immutable and that it was not possible to imagine a conversation between culture and genetics.
You have that one basic string, but it can vibrate in many ways. But we're trying to get a lot of particles because experimental physicists have discovered a lot of particles.
What a deep faith in the rationality of the structure of the world and what a longing to understand even a small glimpse of the reason revealed in the world there must have been in Kepler and Newton to enable them to unravel the mechanism of the heavens in long years of lonely work!
By definition, big data cannot yield complicated descriptions of causality. Especially in healthcare. Almost all of our diseases occur in the intersections of systems in the body.
We need to download scientific journals and upload them to file-sharing networks.
There are many people talking about access to space and, 'How can we make that cheaper? How can we turn that into a Southwest Airlines versus the big airlines?'
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