Premature as the question may be, it is hardly possible not to wonder whether we will find any answer to our deepest questions, any signs of the workings of an interested God, in a final theory. I think that we will not.
Interpretation
The quote reflects skepticism about finding ultimate answers to our deepest existential questions through scientific theories.
Steven Weinberg expresses doubt about the possibility of uncovering profound answers to humanity's most significant queries regarding existence, divinity, and the nature of reality, through the pursuit of a final scientific theory. He seems to suggest that such questions may remain unanswered, despite the progress of science, indicating a limit to what can be known about the universe and perhaps a separation between science and spirituality.
In practice
In a philosophy class discussing the limits of human understanding, this quote can illustrate the tension between science and spirituality.
It was one time when people thought the value of the fine structure constant was important. Now of course it's still important, of course, as a practical matter,but we now know that the value it has is a function, that in any fundamental theory you derive the fine structure constant as a function of all sorts of mass ratios and so on and it's not really that fundamental.
Americans swept away the instruments of English hereditary inequality - entails and titles of nobility - even before we had a constitution.
It's very difficult to convince other countries that they shouldn't pursue nuclear weapons programs if we ourselves are actively developing a component of a strategic defense system.
[Science] is corrosive of religious belief, and it's a good thing too.
With or without religion, you would have good people doing good things and evil people doing evil things. But for good people to do evil things, that takes religion.
I'm offended by the kind of smarmy religiosity that's all around us, perhaps more in America than in Europe, and not really that harmful because it's not really that intense or even that serious, but just... you know after a while you get tired of hearing clergymen giving the invocation at various public celebrations and you feel, haven't we outgrown all this? Do we have to listen to this?
Freemasonry teaches not merely temperance, fortitude, prudence, justice, brotherly love, relief, and truth, but liberty, equality, and fraternity, and it denounces ignorance, superstition, bigotry, lust tyranny and despotism.
We have time to grow old. The air is full of our cries. But habit is a great deadener.
Sane is rich and powerful. Insane is wrong and poor and weak. The rich are free, the poor are put in cages. Res Ipsa Loquitur, amen. Mahalo.
The only people for me are the mad ones, the ones who are mad to live, mad to talk, mad to be saved.
Caesar's wife must be above suspicion.
She suffers as a miser. She must be miserly with her pleasures, as well. I wonder if sometimes she doesn't wish she were free of this monotonous sorrow, of these mutterings which start as soon as she stops singing, if she doesn't wish to suffer once and for all, to drown herself in despair. In any case, it would be impossible for her: she is bound.
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