During the century after Newton, it was still possible for a man of unusual attainments to master all fields of scientific knowledge. But by 1800, this had become entirely impracticable.
Interpretation
The quote highlights the increasing specialization in scientific knowledge over time.
Isaac Asimov points out that during the century following Isaac Newton's discoveries, an individual could potentially gain a comprehensive understanding of all scientific fields. However, by the year 1800, the exponential growth of scientific knowledge made it impossible for any one person to master all disciplines, emphasizing the necessity for specialization in modern science.
In practice
In a lecture on the evolution of scientific understanding, this quote can illustrate the increasing complexity of modern science.
Democracy cannot survive overpopulation. Human dignity cannot survive it. Convenience and decency cannot survive it. As you put more and more people into the world, the value of life not only declines, but it disappears. It doesn't matter if someone dies.
Science does not promise absolute truth, nor does it consider that such a thing necessarily exists. Science does not even promise that everything in the Universe is amenable to the scientific process.
Democracy cannot survive overpopulation.
Although the time of death is approaching me, I am not afraid of dying and going to Hell or (what would be considerably worse) going to the popularized version of Heaven. I expect death to be nothingness and, for removing me from all possible fears of death, I am thankful to atheism.
A subtle thought that is in error may yet give rise to fruitful inquiry that can establish truths of great value.
To bring about destruction by overcrowding, mass starvation, anarchy, the destruction of our most cherished values, there is no need to do anything. We need only do nothing except what comes naturally, and breed. And how easy it is to do nothing
One sometimes finds what one is not looking for. When I woke up just after dawn on Sept. 28, 1928, I certainly didn’t plan to revolutionize all medicine by discovering the world’s first antibiotic, or bacteria killer. But I guess that was exactly what I did.
I think the media can be a very positive influence by essentially holding people to task about the importance of high quality medical care. And when the media is scrutinizing you, then I think that's a very good, positive thing for the field of medicine.
I would designate as science fiction in the best sense: they are visions and anticipations by which we seek to attain a true knowledge, but, in fact, they are only imaginations whereby we seek to draw near to the reality.
If we could honestly promise young couples that we knew how to give them offspring with superior character, why should we assume they would decline? Common sense tells us that if scientists find ways to greatly improve human capabilities, there will no stopping the public from happily seizing them.
At lunch Francis [Crick] winged into the Eagle to tell everyone within hearing distance that we had found the secret of life.
When the sun is sending more energy to earth in one hour than the entire world consumes in a year, any political play to undermine our ability to harness this energy effectively and efficiently is clearly not economical but it's also unethical.
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