Tout est poison, rien n'est poison, tout est une question de dose. Everything is poisonous, nothing is poisonous, it is all a matter of dose.
Claude BernardRead
It is impossible to devise an experiment without a preconceived idea; devising an experiment, we said, is putting a question; we never conceive a question without an idea which invites an answer. I consider it, therefore, an absolute principle that experiments must always be devised in view of a preconceived idea, no matter if the idea be not very clear nor very well defined.
Interpretation
Experiments are based on preconceived ideas, as they stem from questions that need answers.
Claude Bernard emphasizes that the foundation of any scientific experiment is rooted in a preconceived idea or hypothesis. He contends that when we formulate questions to investigate, those questions inherently arise from existing ideas, even if they are not fully formed. This highlights the interplay between thought and inquiry in the scientific method.
In practice
This quote can be used to emphasize the necessity of having a hypothesis in science classes.
Tout est poison, rien n'est poison, tout est une question de dose. Everything is poisonous, nothing is poisonous, it is all a matter of dose.
When a physician is called to a patient, he should decide on the diagnosis, then the prognosis, and then the treatment. ... Physicians must know the evolution of the disease, its duration and gravity in order to predict its course and outcome. Here statistics intervene to guide physicians, by teaching them the proportion of mortal cases, and if observation has also shown that the successful and unsuccessful cases can be recognized by certain signs, then the prognosis is more certain.
The goal of scientific physicians in their own science ... is to reduce the indeterminate. Statistics therefore apply only to cases in which the cause of the facts observed is still indeterminate.
Theories are like a stairway; by climbing, science widens its horizon more and more, because theories embody and necessarily include proportionately more facts as they advance.
True science teaches us to doubt and, in ignorance, to refrain.
Now, a living organism is nothing but a wonderful machine endowed with the most marvellous properties and set going by means of the most complex and delicate mechanism.
The idea of a method that contains firm, unchanging, and absolutely binding principles for conducting the business of science meets considerable difficulty when confronted with the results of historical research. We find, then, that there is not a single rule, however plausible, and however firmly grounded in epistemology, that is not violated at some time or another.
I believe that science is the engine of prosperity, that if you look around at the wealth of civilization today, it's the wealth that comes from science.
Science is composed of laws which were originally based on a small, carefully selected set of observations, often not very accurately measured originally; but the laws have later been found to apply over much wider ranges of observations and much more accurately than the original data justified.
The roads by which men arrive at their insights into celestial matters seem to me almost as worthy of wonder as those matters in themselves.
Agriculture is the backbone of the livelihood security system of nearly 700 million people in the country and we need to build our food security on the foundation of home grown food.
It's often better to read first-rate science fiction than second-rate science - it's far more stimulating, and perhaps no more likely to be wrong.
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