In fast moving fields like cancer, where doctors tailor treatments based on evidence that's constantly evolving, two years can be an eternity of waiting to learn about important science. For some patients, that interval can be fatal.

Although this may seem a paradox, all exact science is dominated by the idea of approximation. When a man tells you that he knows the exact truth about anything, you are safe in inferring that he is an inexact man. Every careful measurement in science is always given with the probable error ... every observer admits that he is likely wrong, and knows about how much wrong he is likely to be.

It is impossible to devise an experiment without a preconceived idea; devising an experiment, we said, is putting a question; we never conceive a question without an idea which invites an answer. I consider it, therefore, an absolute principle that experiments must always be devised in view of a preconceived idea, no matter if the idea be not very clear nor very well defined.

Mathematics is the queen of sciences and number theory is the queen of mathematics. She often condescends to render service to astronomy and other natural sciences, but in all relations she is entitled to the first rank.

Physics is an otherworld thing, it requires a taste for things unseen, even unheard of- a high degree of abstraction... These faculties die off somehow when you grow up... profound curiosity happens when children are young. I think physicists are the Peter Pans of the human race... Once you are sophisticated, you know too much- far too much. Pauli once said to me, "I know a great deal. I know too much. I am a quantum ancient.".

When somebody discovers something like the quadratic formula or the Pythagorean theorem, the convention in science is that he can't control that idea. He has to give it away. He publishes it. What's rewarded in science is dissemination of ideas.